Synthesis and Biological Evaluation of 2′,3′-Dideoxy-3′-Fluororibofuranosyl Purine Nucleosides
✍ Scribed by Poopeiko, Nicolai E.; Khripach, Natalia B.; Kazimierczuk, Zygmunt; Balzarini, Jan; De Clercq, Erik; Mikhailopulo, Igor A.
- Book ID
- 121399141
- Publisher
- Taylor and Francis Group
- Year
- 1997
- Tongue
- English
- Weight
- 225 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0732-8311
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Synthesis and Biological Evaluation of a Series of 2'-Fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides. -A general method for the synthesis of both the cis-and trans-2'-vinylfluoro containing nucleosides is presented. Among the nucleosides prepared compound (XI) displays the best biologica