𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives

✍ Scribed by Judit Esteve; Adriana Lorente; Pedro Romea; Fèlix Urpí; Carla Ríos-Luci; José M. Padrón

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
230 KB
Volume
2011
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

✦ Synopsis

A sequential transformation based on the titanium-mediated aldol addition of (S)-1-bromo-3-(tert-butyldimethylsilyloxy)-2-butanone, a chiral lactate-derived ketone, to tetradecanal followed by reduction of the ensuing aldolate afforded the corresponding syn-1,3-diol as a single diastereomer. Debro-[a]

📜 SIMILAR VOLUMES

Synthesis and biological evaluation of n
Synthesis and biological evaluation of novel methylene-bis-[1,5]-benzodiazepines
✍ M. Raghu; A. Nagaraj; Ch. Sanjeeva Reddy 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 351 KB 👁 1 views

## Abstract magnified image A series of novel methylene‐bis‐chalcones **3** was prepared by the reaction of 5‐(3‐formyl‐4‐hydroxybenzyl)‐2‐hydroxy benzaldehyde **2** with different acetophenones, subsequent treatment of compound **3** with an appropriate __o__‐phenylenediamine gave the correspondi