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Synthesis and Biological Characterization of 1-Methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole Derivatives as Muscarinic Agonists for the Treatment of Neurological Disorders

✍ Scribed by Cao, Yang; Zhang, Minjia; Wu, Cindy; Lee, Selina; Wroblewski, Mary Elizabeth; Whipple, Trisha; Nagy, Peter I.; Takács-Novák, Krisztina; Balázs, Attila; Tőrös, Szilárd; Messer, William S.


Book ID
120585967
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
529 KB
Volume
46
Category
Article
ISSN
0022-2623

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## Abstract A series of 2,5,6‐trisubstituted imidazo[2,1‐__b__][1,3,4]thiadiazoles __via__ Mannich reaction of imidazo[2,1‐__b__][1,3,4]thiadiazoles with morpholine and formaldehyde were synthesized. Structures of all the newly synthesized compounds are well supported by spectral data such as IR, N