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Synthesis and X-ray characterization of 2,5,6-trisubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives

✍ Scribed by Yu-Xia Da; Ji-Hua Zhu; Zhang Zhang; Xiao-Dong Jia; Cai-Xia Yang; Zheng-Jun Quan

Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 119 KB
Volume: 49
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.678

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✦ Synopsis

Abstract

A series of 2,5,6‐trisubstituted imidazo[2,1‐b][1,3,4]thiadiazoles via Mannich reaction of imidazo[2,1‐b][1,3,4]thiadiazoles with morpholine and formaldehyde were synthesized. Structures of all the newly synthesized compounds are well supported by spectral data such as IR, NMR, Mass, and Elemental analysis. Compound 3a has been confirmed by X‐ray diffraction studies. J. Heterocyclic Chem., (2012).

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## Abstract For Abstract see ChemInform Abstract in Full Text.