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Synthesis and biological activity of the 2-amino-4-(4-iodophenyl)amino-6-methylpyrimidine isosteric analogs

✍ Scribed by A. V. Erkin, V. I. Krutikov

Book ID
120771820
Publisher
Springer
Year
2013
Tongue
English
Weight
160 KB
Volume
83
Category
Article
ISSN
1070-3632

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✍ Zhili Zhang; Jie Liu; Weidong Liu; Xiaowei Wang; Zhijian Cheng; Junyi Liu πŸ“‚ Article πŸ“… 2009 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 66 KB

## Abstract magnified image The synthesis of 2‐amino‐4‐hydroxyl‐6‐hydroxymethyl‐5,6,7,8‐tetrahydropyrido[3,2‐d]pyrimidine **3** is described from 2‐amino‐6‐methyluracil **4** through the crucial step of 2‐pivaloyl protecting and cyclization. The assignment of the structure of **3** was performed by