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Synthesis and Biological Activity of Polyethylene Glycol−Mouse Nerve Growth Factor Conjugate

✍ Scribed by Belcheva, Nadya; Woodrow-Mumford, Kim; Mahoney, Melissa J.; Saltzman, W. Mark

Book ID
115477262
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
192 KB
Volume
10
Category
Article
ISSN
1043-1802

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The complete mouse prepro-nerve growth factor (NGF) DNA was fused to the carboxyl terminus of the 6-galactosidase (lac-z) gene of Escherichia coli. Similarly, a genomic fragment encoding the human NGF comprising codons 11 to 106 (from a total of 118) was fused to the fifth codon of the amino terminu