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Synthesis and biological activity of novel sialyl-lewisX conjugates

✍ Scribed by Ulrich Sprengard; Horst Kunz; Christoph Hüls; Wolfgang Schmidt; Dirk Seiffge; Gerhand Kretzshmar


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
332 KB
Volume
6
Category
Article
ISSN
0960-894X

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The synthesis of novel structural analog
✍ Paul V. Murphy; Rod E. Hubbard; David T. Manallack; John G. Montana; Richard J.K 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 240 KB

The synthesis of conformationally rigid tetralin-based mimics of the tetrasaccharide sialyl Lewis x are described. Palladium catalysed coupling reactions are employed in the key synthetic steps.