Synthesis and biological activity of 4-amino-3-cyano-1,2-dihydrospiro [naphthalene-2,1′-cyclohexane]
✍ Scribed by A. I. Markosyan; M. G. Oganisyan; R. A. Kuroyan; N. L. Grigoryan; R. S. Sukasyan; É. M. Arzanunts; I. S. Sarkisyan; A. A. Chachoyan; B. T. Garibdzhanyan
- Book ID
- 112405112
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 352 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0091-150X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Depending on the experimental conditions the spirolactone **3** on treatment with methylamine gave compounds **6, 7** or the rearranged product **4**. Compound **4** was used to prepare the title compounds **11–13, 15, 18–20** and other derivatives.
New derivatives of 3,4-dihydrospiro[cycloalkane- \(1^{\prime}, 2(1 H)\)-quinolines] were obtained from cycloheptanone and cyclooctanone via facile three steps hetero spiro annulation process. Their nitro derivatives were prepared through electrophilic substitution reactions.