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Synthesis and biological activities of new analogues of thymopoietin II (32–36)

✍ Scribed by Nawrocka-Bolewska, Eleonora ;Siemion, Ignacy Z. ;Mihelić, Mirna ;Voelter, Wolfgang


Book ID
102367091
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
284 KB
Volume
1990
Category
Article
ISSN
0947-3440

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✦ Synopsis


Abstract

The pentapeptide fragment of thymopoietin II (32–36) (TP5) shows similar biological activities as the parent molecule, also induces E‐rosette formation, and enhances phagocytosis. In order to elucidate further structural and functional requirements for its activity we decided to replace each amino acid residue of the pentapeptide by proline moieties.


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