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Synthesis and Biodistribution of 8-Iodo-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]-diazepine: Iozapine.

✍ Scribed by Alummoottil V. Joshua; Sanjay K. Sharma; Alicia Strelkov; John R. Scott; Mathew T. Martin-Iverson; Douglas N. Abrams; Peter H. Silverstone; Alexander J. B. McEwan


Publisher
John Wiley and Sons
Year
2007
Weight
22 KB
Volume
38
Category
Article
ISSN
0931-7597

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New 5- e][1,4]diazepin-11-ones with Antiarrhythmic Activity. -The tested compounds (I) show antiarrhythmic activity in various testing models. Especially noteworthy is that therapy of bradycardic arrhythmics occurs without decrease of heart rate.