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Synthesis and Biochemical Properties of Cyanuric Acid Nucleoside-Containing DNA Oligomers

✍ Scribed by Gasparutto, Didier; Da Cruz, Sandrine; Bourdat, Anne-Gaëlle; Jaquinod, Michel; Cadet, Jean

Book ID
120219586
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
133 KB
Volume
12
Category
Article
ISSN
0893-228X

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✍ B Nawrot; O Michalak; M Nowak; A Okruszek; M Dera; W.J Stec 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 85 KB

Novel analogues of acyclic nucleosides based on a bis(hydroxymethyl)phosphinic acid (BHPA) backbone were obtained by condensation of the bis(4,4%-dimethoxytrityl) derivative of BHPA with N-1-or N-3-(2-hydroxyethyl)thymine in the presence of MSNT, or by an Appel reaction with N-1-or N-3-(2-aminoethyl