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Synthesis and bioactivity of novel triazolo [1,5-a]pyrimidine derivatives[3]

✍ Scribed by Guangfu Yang; Li Xu; Aihong Lu

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
284 KB
Volume
12
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

In an attempt to discover novel compounds with high herbicidal activity and low toxicity, a series of novel 1,2,4‐triazolo[1,5‐a]pyrimidine derivatives, α‐(5,7‐dimethyl‐1,2,4‐triazolo[1,5‐a]pyrimidine‐2‐thio)acetamides 3 and α‐(5,7‐dimethyl‐1,2,4‐triazolo[1,5‐a]pyrimidine‐2‐sul‐fonyl)acetamides 4, have been designed and synthesized by a three‐step synthetic route. The structures of all compounds prepared were confirmed by elemental analyses and by ^1^H NMR and mass spectroscopy. The results of preliminary bioassay indicate that the title compounds possess good herbicidal activity against rape (Brassica campestris L.) and barnyardgrass (Echinochloca crusgalli L.) © 2001 John Wiley & Sons, Inc. Heteroatom Chem 12:491–496, 2001

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