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Synthesis and Antimicrobial Evaluation of Novel Pyrazolo[1,5-a]pyrimidine, Triazolo[1,5-a]pyrimidine and Pyrimido[1,2-a]benzimidazole Derivatives.

✍ Scribed by Mohamed R. Shaaban; Tamer S. Saleh; Ahmad M. Farag


Publisher
John Wiley and Sons
Year
2007
Weight
32 KB
Volume
38
Category
Article
ISSN
0931-7597

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Abstract

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## 2-Acetylbenzothiazole (1) reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the enaminone 2. Compound 2 reacts regioselectively with some nitrilimines 5a-d and nitrile oxides 6b-d to afford the novel pyrazole and isoxazole derivatives 11a-d and 12b-d, respectively, which react wi