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Synthesis and Bio-activities of Pyrazolyl or Pyridinyl Substituted Tonghaosu Analogs

โœ Scribed by Biao-Lin Yin; Li Chen; Han-Hong Xu; Jian-Cun Zhang; Yu-Lin Wu

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
70 KB
Volume
25
Category
Article
ISSN
0256-7660

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## Abstract Four series of 1 __H__โ€pyrazole derivatives have been synthesized. The first series was synthesized starting with the reaction of 3โ€(5โ€bromoโ€2โ€thienyl)โ€1โ€phenylโ€1 __H__โ€pyrazoleโ€4โ€carboxaldehyde **1** with Lโ€serine, Lโ€cysteine, or Lโ€penicillamine, followed by __N__โ€protection using (Boc