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ChemInform Abstract: New Aromatase Inhibitors. Synthesis and Inhibitory Activity of Pyridinyl-Substituted Flavanone Derivatives.

โœ Scribed by Christelle Pouget; Catherine Fagnere; Jean-Philippe Basly; Gerard Habrioux; Albert-Jose Chulia

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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Synthesis of 5-Substituted Quinazolinone Derivatives and Their Inhibitory Activity in vitro. -Quinazolinone derivatives (IV) and their methyl esters (III) are synthesized and evaluated as nonclassical lipophilic inhibitors of thymidylate synthase (no yields are given). -(BAEK, DU-