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Synthesis and Assay of Isoquinoline Derivatives as HIV-1 Tat—TAR Interaction Inhibitors.

✍ Scribed by Meizi He; Dekai Yuan; Wei Lin; Ruifang Pang; Xiaolin Yu; Ming Yang


Publisher
John Wiley and Sons
Year
2005
Weight
12 KB
Volume
36
Category
Article
ISSN
0931-7597

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2-Phenylquinolones as Inhibitors of the
✍ Barbara Gatto; Oriana Tabarrini; Serena Massari; Giulia Giaretta; Stefano Sabati 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB

## Abstract **Novel 2‐phenylquinolones** aimed at the Tat–TAR complex were synthesized and tested. Derivatives characterized by precise modifications of the quinolone nucleus and to the side chain of the 2‐phenyl ring allowed a thorough structure–activity study, confirming 2‐phenylquinolone as a su