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Synthesis and applications of nonracemic β-amino aldehydes to the asymmetric synthesis of piperdines: (+)-dihydropinidine

✍ Scribed by Franklin A Davis; Joanna M Szewczyk


Book ID
104259648
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
242 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


New methodology for the enantioselective synthesis of stable N-protected 13-amino aldehydes 5 and 6, and their application to the asymmetric synthesis of (+)-2-phenylpiperdine ( 11) and (+)-dihydropinidine ( 14) is described.


📜 SIMILAR VOLUMES


ChemInform Abstract: Synthesis and Appli
✍ F. A. DAVIS; J. M. SZEWCZYK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

Synthesis and Applications of Nonracemic β-Amino Aldehydes to the Asymmetric Synthesis of Piperidines: (+)-Dihydropinidine. -A new method to synthesize chiral building blocks, i.e. the stable N-protected β-aminoaldehydes (VI), in 4 steps is reported. They are applied in the synthesis of the piperid