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Synthesis and Application of Chiral Cyclopropane-Based Ligands in Palladium-Catalyzed Allylic Alkylation

✍ Scribed by Molander, Gary A.; Burke, Jason P.; Carroll, Patrick J.


Book ID
127186205
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
322 KB
Volume
69
Category
Article
ISSN
0022-3263

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Novel planar chiral P,N-[2.2]paracycloph
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A series of planar chiral P,N-[2.2]paracyclophane ligands were synthesized and applied in enantioselective palladiumcatalyzed allylic alkylation, in which the central chirality of [2.2]paracyclophane is the dominant stereocontrol element. The effect of the substituents attached to the phosphorus ato