𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and antiviral activity of fluoro sugar nucleosides 2: Synthesis and biological evaluations of 2′, 3′-dideoxy-2′-fluoro-3′-C-hydroxymethyl-β-D-arabinofuranosyl nucleosides

✍ Scribed by Moon Woo Chun; Kyung Lee; Yong Suk Choi; Jeewoo Lee; Joong Hyup Kim; Chong Kyo Lee; Bo Gil Choi; Yong Can Xu


Book ID
112961267
Publisher
Springer
Year
1996
Tongue
English
Weight
272 KB
Volume
19
Category
Article
ISSN
0253-6269

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of Potentially Antiviral 2′,3′
✍ Songqing Wang; Junbiao Chang; Shifeng Pan; Kang Zhao 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 205 KB

## Abstract A series of novel 3′‐(alkyl(hydroxy)amino)‐2′‐fluoronucleoside analogs were prepared __via__ conjugate addition of __N__‐methylhydroxylamine to various 2‐fluorobutenolides. The adducts **13a** and **16** were obtained as single isomers under absolute control of stereochemistry. The cruc

Synthesis and antiviral evaluation of α-
✍ Kohei Yamada; Hiroyuki Hayakawa; Shinji Sakata; Noriyuki Ashida; Yuichi Yoshimur 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 427 KB

We have identified a selective S(N)2' reaction triggered by iodide ion that leads to the ring-opening of 2,2'-anhydro-α-nucleosides. By applying the method, we have synthesized α-D-2',3'-didehydro-2',3'-dideoxy-3'-C-hydroxymethyl nucleosides, designed as potential antiviral agents.