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Synthesis and antitumor activity of simple vinyl and .alpha.-methylene-.gamma.-butyrolactone sulfonate esters and silyl enol ethers

โœ Scribed by Stang, Peter J.; Treptow, Warren L.


Book ID
126986712
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
651 KB
Volume
24
Category
Article
ISSN
0022-2623

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Sly1 enol ethers of ketones are alkylated with ethyl a-chloro-a-phenylseleno acetate la or with ethyl a-chloro-a-phenylseleno propionate lb, mediated by zinc bromide to give the corresponding a-phenylseleno-y-keto esters 3 in moderate to good yields.