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Synthesis and Antitumor Activity of a Series of Cyclic Amidines of 2,3-Dihydro-1H-1,5-benzodiazepines.

✍ Scribed by Regina Janciene; Lidija Kosychova; Virginija Bukelskiene; Vigintas Domkus; Zita Stumbreviciute; Vida Ragaleviciene; Benedikta D. Puodziunaite


Book ID
101931187
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: 2,3-Dihydro-1H-1,5-
✍ B. PUODZIUNAITE; L. KOSYCHOVA; R. JANCIENE; Z. STUMBREVICIUTE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 1 views

## 12 -132 2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines. -Benzodiazepinone derivatives (I) are transformed into the corresponding thiolactams (II), which can be converted to a new series of diversely substituted amidines [cf. (IV), (V)]. Ammonia, primary amines and h