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Synthesis and antitumor activity of 1-β-D-arabinofuranosylcytosine-5′-diphosphate-prednisolone and -cortisol

✍ Scribed by Chung Il Hong; Alexander Nechaev; Charles R. West

Book ID: 118314500
Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 490 KB
Volume: 94
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(80)90542-2

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## Abstract The cytotoxicity of many antitumor agents exhibits cell‐cycle phase specificity. Using a human lymphoma cell line synchronized by thymidine block, we have investigated the differential uptake of radioactive 1‐β‐D‐arabinofuranosylcytosine (ara‐C) and prednisolone in various phases of the