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Synthesis and antituberculosis activity of some new 2-quinoxalinecarbonitriles

✍ Scribed by M.Elena Montoya; Yolanda Sainz; M.Angel Ortega; Adela Lopez De Cerain; Antonio Monge


Book ID
114019412
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
166 KB
Volume
53
Category
Article
ISSN
0014-827X

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ChemInform Abstract: Synthesis and Antit
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Synthesis and Antituberculosis Activity of New 2-Quinoxalinecarbonitrile 1,4-Di-N-oxides. -In continuation of a recent work novel types of the title compounds such as (III) are synthesized. On the basis of the biological results such compounds may be a new type of substances in the treatment of tube

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acids families with cyclic and acyclic amines and demonstrate for the first time the activity of these compounds as antituberculosis agents against Mycobacterium tuberculosis H 37 Rv, M. tuberculosis rifampicin resistance (ATCC 35338), and M. tuberculosis isoniazid resistance (ATCC 35822). The fatty