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Synthesis and Antisense Properties of Oligodeoxyribonucleotides Containing C5-Substituted Arabinofuranosyluracil.

✍ Scribed by Hiroaki Ozaki; Kiyohiro Nakajima; Masayasu Kuwahara; Hiroaki Sawai

Publisher
John Wiley and Sons
Year
2004
Weight
52 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 77 KB 👁 1 views

## Abstract Several 2′‐deoxy‐2′‐[^18^F]fluoro‐1‐__β__‐D‐arabinofuranosyluracil derivatives have been synthesized. Coupling of 1‐bromo‐2‐deoxy‐2‐[^18^F]fluoro‐3,5‐di‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** with protected uracil derivatives **3a–e** followed by hydrolysis and high‐performance liquid