𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Antiprotozoal Evaluation of New N4-(Benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones)

✍ Scribed by Julieta Coro; Susan Little; Vanessa Yardley; Margarita Suárez; Hortensia Rodríguez; Nazario Martín; Rolando Perez-Pineiro

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
355 KB
Volume
341
Category
Article
ISSN
0365-6233

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The synthesis and in‐vitro antiprotozoal evaluation of novel N^4^‐(benzyl)spermidyl‐linked bis(1,3,5‐thiadiazinane‐2‐thione) (bis‐THTT) derivatives from N^4^‐(benzyl)spermidine is disclosed. Several of the new bis‐THTT have in‐vitro activities against L. donovani and T. cruzi that are comparable or superior to those of currently employed protozoocidal agents.

📜 SIMILAR VOLUMES

Syntheses of some new 4-amino-5-(N-methy
Syntheses of some new 4-amino-5-(N-methyl-arylsulfonamido)methyl-1,2,4-triazole-3-thiones and their derivatives
✍ Guofeng Jia; Zhengming Li 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 1 views

## The cyclization of 4-arnino-5-(N-methyl-arylsulfonarnido) methyl-1,2,4-triazole-3-thiones 11, synthesized by the Reid and Heindel approach, with a-chloroacetophenone yields 7H-6-aryl-3-(N-rnethyl-arylsulfonarnido) methyl-s-triazob[3,4-b][l, 3,4]-thiazines 111. Novel compounds I1 also react with

Synthesis and Antimicrobial Properties o
Synthesis and Antimicrobial Properties of New 4-(Alkylidene/arylidene)-amino-5-(2-furanyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones and 6-Aryl-3-(2-furanyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines
✍ Nedime Ergenç; Nuray Ulusoy; Gültaze Çapan; Gülten Ötük Sanis; Muammer Kiraz 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB 👁 2 views

A series of 4-(alkylidene/arylidene)amino-5-(2-furanyl)-2.4-dihydro-3H-I .2.4-triazolc-3-1hiones (2) and 6-aryl-3-(2-furanyl)-7H-12.4-triazolo[3,4-b]( 1.3.41 thiadiazines (3) werc synthesized. The configuration of 2g was assigned on che basis of 'H-NMR data. Of the new derivatives tesced. only 2b. 2

Synthesis and Crystal Structures of Bis(
Synthesis and Crystal Structures of Bis(tetraethylammonium)(2-oxo-1,3-dithiole-4,5-dithiolato)zincate(II) and Bis(tetra-n-butylammonium)(2-oxo-1,3-dithiole-4,5-dithiolato)zincate(II)
✍ Harald Müller; Anna Puig Molina; B. Zh. Narymbetov; L. V. Zorina; S. S. Khasanov 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 German ⚖ 112 KB 👁 1 views

The title compounds were prepared from 1,3,4,6tetrathiapentalene-2,5-dione (1) in one step via the in situ The X-ray single crystal structure of (Et 4 N) 2 [Zn(dmid) 2 ] (3 a) gave the tetragonal space group P4 3 2 1 2 with a = b = 13.810(2) A Ê , c = 16.480(3) A Ê , and Z = 4. (n-Bu 4 N) 2 [Zn(dmi