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Synthesis and antiprotozoal activity of 1,2,3,4-tetrahydro-2-thioxopyrimidine analogs of combretastatin A-4

✍ Scribed by Dereje Desta; Robert Sjoholm; Lauren Lee; Megan Lee; Kristin Dittenhafer; Sarah Canche; Balaji Babu; Sameer Chavda; Christie Dewar; Stephanie Yanow; Aaron A. Best; Moses Lee


Book ID
105771094
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
337 KB
Volume
20
Category
Article
ISSN
1054-2523

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✍ Esvet Akbał; Furgan Aslanoǧlu; Ahmet Şener; Bariş Anil 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 319 KB

## Abstract magnified image 5‐Benzoyl‐4‐(substituted phenyl)‐6‐phenyl‐1,2,3,4‐tetrahydro‐2‐thioxopyrimidines (**4a‐d**) were synthesized using the Biginelli three component cyclocondensation reaction of an appropriate β‐diketone, arylaldehyde, and thiourea in acetic acid under reflux condition in