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Synthesis and Antiproliferative Activity of a New Compound Containing an α-Methylene-γ-Lactone Group

✍ Scribed by González, Antonio G.; Silva, Margarita Hernández; Padrón, Juan I.; León, Francisco; Reyes, Eduardo; Álvarez-Mon, Melchor; Pivel, Juan P.; Quintana, José; Estévez, Francisco; Bermejo, Jaime


Book ID
126042406
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
89 KB
Volume
45
Category
Article
ISSN
0022-2623

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Synthesis and antiproliferative activity
✍ Nowicka, Anna; Liszkiewicz, Hanna; Nawrocka, Wanda P.; Wietrzyk, Joanna; Kempińs 📂 Article 📅 2014 🏛 SP Versita 🌐 English ⚖ 616 KB

## Abstract A series of pyrimido[1,2-a]benzimidazole and α-cyanocinnamic acid derivatives have been synthesized in the reactions of Schiff bases 2–7 with selected nitriles containing an active methylene group: malononitrile 8–12, cyanoacetamide 13–16, benzyl cyanide 17–21, benzoylacetonitrile 22–24