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Synthesis and antiproliferative activityin vitroof new 2-aminobenzimidazole derivatives. Reaction of 2-arylideneaminobenzimidazole with selected nitriles containing active methylene group

✍ Scribed by Nowicka, Anna; Liszkiewicz, Hanna; Nawrocka, Wanda P.; Wietrzyk, Joanna; Kempińska, Katarzyna; Dryś, Andrzej

Book ID
121821156
Publisher
SP Versita
Year
2014
Tongue
English
Weight
616 KB
Volume
12
Category
Article
ISSN
1895-1066

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Synthesis and antiproliferative activity
Synthesis and antiproliferative activityin vitroof new 2-aminobenzimidazole derivatives. Reaction of 2-arylideneaminobenzimidazole with selected nitriles containing active methylene group
✍ Nowicka, Anna; Liszkiewicz, Hanna; Nawrocka, Wanda P.; Wietrzyk, Joanna; Kempińs 📂 Article 📅 2014 🏛 SP Versita 🌐 English ⚖ 616 KB

## Abstract A series of pyrimido[1,2-a]benzimidazole and α-cyanocinnamic acid derivatives have been synthesized in the reactions of Schiff bases 2–7 with selected nitriles containing an active methylene group: malononitrile 8–12, cyanoacetamide 13–16, benzyl cyanide 17–21, benzoylacetonitrile 22–24