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Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives

✍ Scribed by Wanda Nawrocka; Barbara Sztuba; Maria W Kowalska; Hanna Liszkiewicz; Joanna Wietrzyk; Anna Nasulewicz; Marzena Pełczyńska; Adam Opolski

Book ID: 113619671
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 246 KB
Volume: 59
Category: Article
ISSN: 0014-827X
DOI: 10.1016/j.farmac.2003.12.001

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## Abstract A series of pyrimido[1,2-a]benzimidazole and α-cyanocinnamic acid derivatives have been synthesized in the reactions of Schiff bases 2–7 with selected nitriles containing an active methylene group: malononitrile 8–12, cyanoacetamide 13–16, benzyl cyanide 17–21, benzoylacetonitrile 22–24