Synthesis and antiplatelet activity of DMP 757 analogs
โ Scribed by John Wityak; John M. Fevig; Sharon A. Jackson; Alexander L. Johnson; Shaker A. Mousa; Anju Parthasarathy; Gregory J. Wells; William F. DeGrado; Ruth R. Wexler
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 208 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0960-894X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
A series of 11 asparagines substituted on N4 was prepared and evaluated for their ability to inhibit the growth of L5178Y leukemia cell cultures. These cells require an exogenous source of L-asparagine and should be sensitive to an asparagine antimetabolite. The compounds were prepared by reaction o