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Synthesis and Antiplasmodial Activity of Highly Active Reverse Analogues of the Antimalarial Drug Candidate Fosmidomycin

✍ Scribed by Christoph T. Behrendt; Andrea Kunfermann; Dr. Victoria Illarionova; An Matheeussen; Dr. Tobias Gräwert; Prof. Michael Groll; Dr. Felix Rohdich; Prof. Adelbert Bacher; Dr. Wolfgang Eisenreich; Prof. Dr. Markus Fischer; Prof. Dr. Louis Maes; Prof. Dr. Thomas Kurz


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
232 KB
Volume
5
Category
Article
ISSN
1860-7179

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ChemInform Abstract: Design, Synthesis,
✍ J. N. CUMMING; D. WANG; S. B. PARK; T. A. SHAPIRO; G. H. POSNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

Alcohol Analogues of the Antimalarial Artemisinin. -A series of the title compounds such as (VIII)-(XI) is synthesized and used in the preparation of derivatives such as (XIII). These products are potent antimalarials with up to 140% of the efficacy of the natural artemisinin. -(CUMMING,