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Synthesis and antimycobacterial evaluation of various 6-substituted pyrazolo[3,4- d ]pyrimidine derivatives

✍ Scribed by Trivedi, Amit; Vaghasiya, Shailesh; Dholariya, Bipin; Dodiya, Dipti; Shah, Viresh

Book ID
121876829
Publisher
Informa plc
Year
2010
Tongue
English
Weight
652 KB
Volume
25
Category
Article
ISSN
1475-6366

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A convenient synthesis of pyrazolo[3,4-d
A convenient synthesis of pyrazolo[3,4-d]pyrimidine-4,6-dione and pyrazolo[4,3-d]pyrimidine-5,7-dione derivatives
✍ M. El Haddad; M. Soukri; S. Lazar; A. Bennamara; G. Guillaumet; M. Akssira πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 470 KB

## Abstract Pyrazolo‐[3,4‐__d__]pyrimidine‐4,6‐diones **5** and pyrazolo[4,3‐__d__]pyrimidine‐5,7‐diones **7** were synthesized by Curtius rearrangement of pyrazolic mono‐esters **2** and **3** followed by hetero‐cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.