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Synthesis and antimicrobial evaluation of 3-methanone-6-substituted-benzofuran derivatives

✍ Scribed by Liu, Jingbao; Jiang, Faqin; Jiang, Xizhen; Zhang, Wei; Liu, Jingjing; Liu, Wenlu; Fu, Lei


Book ID
119234008
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
399 KB
Volume
54
Category
Article
ISSN
0223-5234

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## Abstract The reaction of ethyl 4‐(benzofuran‐2‐yl)‐2,4‐dioxobutanoate **2** with two moles of hydrazine hydrate afforded 5‐(benzofuran‐2‐yl)‐1__H__‐pyrazole‐3‐carbohydrazide **4a**, while its reaction with equimolar amount of phenylhydrazine gave ester **3b** which then converted to 5‐(benzofura