𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and antimicrobial activity of tris phosphonates

✍ Scribed by B. Siva Kumar; M. Veera Narayana Reddy; G. Chandra Sekhar Reddy; N. Bakthavatchala Reddy; C. Suresh Reddy

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
99 KB
Volume
48
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Syntheses of novel [{(3‐dialkoxy‐phosphoryl)‐(substituted‐phenyl‐methyl)‐2‐oxo‐2‐phenyl‐2,3‐dihydro‐2λ^5^–benzo [1,3,2] diazaphosphol‐1‐yl}‐(substituted‐phenyl)‐methyl]‐phosphonic acid diethyl/dimethyl esters (3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j) were conveniently accomplished by cyclocondensation of [(2‐{(dimethoxy‐phosphoryl)‐phenyl‐methyl)‐amino}‐phenyl amino)‐phenyl‐methyl]phosphonic acid diethyl/dimethyl esters (2a, 2b, 2c, 2d, 2e, 2f, 2g, 2h, 2i, 2j) with phenyl phosphonic dichloride in dry toluene in the presence of triethylamine at 40°C. The title compounds were characterized by physicospectral techniques. All the synthesized compounds were found to possess antimicrobial properties. J. Heterocyclic Chem., 2011.

📜 SIMILAR VOLUMES

Synthesis, characterization, and evaluat
Synthesis, characterization, and evaluation of antimicrobial activities of a new class of macrocyclic phosphonates
✍ G. Chandra Sekhar Reddy; A. Uma Ravi Sankar; M. Veera Narayana Reddy; C. Radha R 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 117 KB 👁 1 views

## Abstract A series of a new class of phosphorus analogue macrocycles was accomplished by condensation of N‐substituted‐[bis(3,5‐dimethyl‐2‐hydroxybenzyl)]‐amines with various phosphorus dichlorides in dry toluene in the presence of triethylamine at 0–50°C. All the title compounds were evaluated f