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Synthesis and Antimicrobial Activity of Some New 5-Nitrofuran Derivatives

✍ Scribed by Paola Roveri; Vanni Cavrini; Rita Gatti; Fabrizio Bianucci; Paolo Legnani

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
193 KB
Volume
315
Category
Article
ISSN
0365-6233

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✦ Synopsis

Abstract

Starting from 5‐nitro‐2‐furoyl azide (1), some new 5‐nitro‐2‐furamides 2a–d, O‐alkyl N‐(5‐nitro‐2‐furyl)carbamates 3a,b and 5‐nitro‐2‐ureidofurans 4a,b were synthesized and tested for in vitro antimicrobial activity. Compounds 2c and 2d exhibited appreciable activity against S. pyogenes and S. aureus.

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