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Synthesis and antimicrobial activity of novel quinazolone derivatives

✍ Scribed by N. S. Habib; M. A. Khali

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
429 KB
Volume
73
Category
Article
ISSN
0022-3549

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✦ Synopsis

Three novel series of 4-oxoquinazoline derivatives were prepared and evaluated as potential antimicrobial agents. Evaluation of the antimicrobial activity of a variety of 4-substituted-1-thiosemicarbazides, 3,4-disubstituted thiazolines, and 3-substituted-5-thiazolidones reveals that the majority possess significant in vitro activity against Gram-positive organisms. Some derivatives also exhibited antifungal activity.

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One-pot synthesis and antimicrobial acti
One-pot synthesis and antimicrobial activity of novel quinolone heterocyclic derivatives
✍ Hui Zheng; Juan Liu; Pengfei Zhang πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 149 KB

## Abstract magnified image A series of novel quinolone heterocyclic derivatives from natural amino acid were synthesized in one‐pot method, which is very beneficial for the industrial operation to save manufacturing costs. These new compounds were characterized by ^1^H NMR, ^13^C NMR, infrared spe