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One-pot synthesis and antimicrobial activity of novel quinolone heterocyclic derivatives

✍ Scribed by Hui Zheng; Juan Liu; Pengfei Zhang

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
149 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image A series of novel quinolone heterocyclic derivatives from natural amino acid were synthesized in one‐pot method, which is very beneficial for the industrial operation to save manufacturing costs. These new compounds were characterized by ^1^H NMR, ^13^C NMR, infrared spectrum, mass spectrum, and elemental analysis. The preliminary bioassays results revealed that they had certain antimicrobial activity against Bacillus subtilis and Staphylococcus aureus. J. Heterocyclic Chem., (2010).

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