✦ LIBER ✦

Synthesis and antimicrobial activity of novel 2-alkyl/arylcarbamato-6-(1,1-dimethylethyl)-3-cyclohexyl-3,4-dihydro-2H-1,3,2-benzoxazaphosphorine-2-oxides

✍ Scribed by Y. Hari Babu; P. Vasu Govardhana Reddy; C. Suresh Reddy; C. Devendranath Reddy; P. Uma Maheswari Devi

Publisher: Journal of Heterocyclic Chemistry
Year: 2002
Tongue: English
Weight: 45 KB
Volume: 39
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570390529

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Novel 2‐alkyl/arylcarbamato‐6‐(1,1‐dimethylethyl)‐3‐cyclohexyl‐3,4‐dihydro‐2__H__‐1,3,2‐benzoxaza‐phosphorine‐2‐oxides (IV) have been synthesized from reactions of 2‐cyclohexylaminomethyl‐4‐t‐butylphenol I [8c] with various dichlorophosphinyl carbamates (III) [8a‐b] in dry toluene in the presence of triethylamine at 40‐50 °C. All the title compounds (IVa‐j) at reflux temperature are degraded to 2‐amino‐6‐(1,1‐dimethylethyl)‐3‐cyclohexyl‐3,4‐dihydro‐2__H__‐1,3,2‐benzoxazaphosphorine‐2‐oxide (IVk) exclusively. The structures are determined by ir, nmr and mass spectral studies. They were screened for antifungal activity against Penicillium notatum, Aspergillus niger and Helminthosporium sps, and antibacterial activity on Escherchia coli, Staphylococcus aureus and Pseudomonas aeruginosa. A few of them possess significant activity.

📜 SIMILAR VOLUMES

Synthesis and Antimicrobial Activity of

Synthesis and Antimicrobial Activity of Novel 2-Alkyl/Arylcarbamato-6- (1,1-dimethylethyl) -3-cyclohexyl-3,4-dihydro-2H-1,3,2-benzoxazaphosphorine-2-oxides.

✍ Y. Hari Babu; P. Vasu Govardhana Reddy; C. Suresh Reddy; C. Devendranath Reddy; 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 112 KB 👁 2 views

## Abstract For Abstract see ChemInform Abstract in Full Text.

Synthesis and antimicrobial activity of

Synthesis and antimicrobial activity of 2-substituted-2,3-dihydro-5-propoxy-1H-1,3,2-benzodiazaphosphole 2-Oxides

✍ M. Venugopal; B. Sankar Reddy; C. Devendranath Reddy; K. D. Berlin 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 117 KB 👁 1 views

## Abstract Several 2‐alkylcarbamato/thiocarbamato/aryloxy/trichloromethyl‐2,3‐dihydro‐5‐propoxy‐1__H__‐1,3,2‐benzodiazaphosphole 2‐oxides (**4** and **6**) were synthesised by reacting 4‐propoxy‐__o__‐phenylenediamine (**1**) with various __N__‐dichlorophosphinyl carbamates (**3**), aryl phosphoro

13C and 31P NMR data for some 6-aryloxyd

13C and 31P NMR data for some 6-aryloxydibenzo[d, f][1,3,2] dioxaphosphepin 6-oxides/sulphides and 3-cyclohexyl-6-(1, 1-dimethylethyl)-3, 4-dihydro-2-aryloxy-2h-1,3,2-benz-oxazaphosphorine 2-oxides

✍ M. S. R. Naidu; C. Naga Raju 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 295 KB

13C And 31P NMR chemical shifts and 13C-3'P coupling constants of 26 6-aryloxydibenzo oxides are reported. The assignments are supported by SFORD spectra.

Synthesis and Bioactivity of Some New 2-

Synthesis and Bioactivity of Some New 2-Substituted-3,4-dihydro-3-(3′-chloro-4′-fluorophenyl)-2H- [1,3,2]benzoxazaphosphorin 2-Oxides.

✍ Y. B. Kiran; M. Kasthuraiah; C. Nagaraju; D. Gunasekar; S. V. S. Madhu Babu; C. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

Synthesis and Antimicrobial Activity of

Synthesis and Antimicrobial Activity of Some New N-(Substituted phenyl)-N′- [2,3-dihydro-2-oxido-3-(4′-fluorophenyl)-1H-(1,3,2)benzoxazaphosphorin 2-yl]ureas.

✍ P. Haranath; V. Sreedhar Kumar; C. Suresh Reddy; C. Naga Raju; C. Devendranath R 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Synthesis and antimicrobial activity of

Synthesis and antimicrobial activity of some new N-(substituted phenyl)-N′-[2,3-dihydro-2-oxido-3-(4′-fluorophenyl)-1H-(1,3,2)benzoxazaphosphorin 2-yl]ureas

✍ P. Haranath; V. Sreedhar Kumar; C. Suresh Reddy; C. Naga Raju; C. Devendranath R 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 331 KB 👁 1 views

## Abstract magnified image Substituted benzoxazaphosphorin 2‐yl ureas were synthesized by reacting 2‐(4‐fluoro‐phenylamino)‐methylphenol (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45‐50 °C and characterized by spectral data. Thes