Synthesis and antimicrobial activity of N-(substituted)-N-[1,2,4,8,10,11-hexachloro-6-oxido-12H-dibenzo(d,g)(1,3,2)-dioxaphosphocin-6-yl]ureas
✍ Scribed by P. Haranath; U. Anasuyamma; P. Vasu Govardhana Reddy; C. Sureshx Reddy
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2004
- Tongue
- English
- Weight
- 40 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Substituted dibenzo dioxaphosphocin‐6‐yl ureas were synthesized by reacting hexachlorophene (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45‐50 ^o^C. Their IR, ^1^H, ^13^C and ^31^P NMR spectral data is discussed. These compounds were found to possess good antimicrobial activity.
📜 SIMILAR VOLUMES
Syitliesis of several 6-sicbstittcted-I ,2,4,8,10.1 I -hexachloro-1 ZH-dibeiizo[d,g][l,3,2]dioxaphosphocin 6oxides and their IR. IH, I3C, and 31P N M R aizd inass spectral analyses are described. Observation of geminal coupling ['J(H,H, = 16.0 Hz] between bridged methylene protons ( 1 2-CH2) suggest
## Abstract __N__‐Substituted N′‐[6‐methyl‐2‐oxido‐1,3,2‐dioxaphosphinino(5,4,‐b)pyridine‐2‐yl]ureas have been accomplished by condensation of equimolar quantities of chlorides of various carbamidophosphoric acids (**__3__**) with 3‐hydroxyl‐6‐methyl‐2‐pyridinemethanol (lutidine diol) (**__4__**) i