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Synthesis and antiinflammatory activity of novel indazolones

โœ Scribed by Khaled A. M. Abouzid; H. S. El-Abhar


Book ID
105726106
Publisher
Springer
Year
2003
Tongue
English
Weight
852 KB
Volume
26
Category
Article
ISSN
0253-6269

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Recently we identified three promising topically active antiinflammatory agents (2, 3, and 4) from a series of racemic aryl-sphingolipids that inhibit protein kinase C (PKC). We now wish to report the enantioselective synthesis of the aforementioned leads and their comparative biological profile. Th