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Synthesis and antifungal evaluation of 6-hydroxy-1H-carbazole-1,4(9H)-diones

✍ Scribed by Chung-Kyu Ryu; Seung-Yon Lee; Na Young Kim; Jung An Hong; Joo Hee Yoon; Aram Kim

Book ID: 104005071
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 259 KB
Volume: 21
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2010.10.124

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✦ Synopsis

6-Hydroxy-1H-carbazole-1,4(9H)-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that 6-hydroxy-1H-carbazole-1,4(9H)-diones would be potent antifungal agents.

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