A Synthesis of 9-Methoxy-1-Methyl-1H,6H-Pyrazolo[4,3-c]Carbazole
✍ Scribed by Morel, Sandrine; Boyer, Gérard; Coullet, Fabien; Galy, Jean-Pierre
- Book ID
- 111906643
- Publisher
- Taylor and Francis Group
- Year
- 1996
- Tongue
- English
- Weight
- 233 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0039-7911
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The carbazole unit of the title molecule, C 15 H 15 NO 3 , is not planar. The dihedral angle between the benzene ring and the fused pyrrole ring is 0.9 (1) . The cyclohexene ring is in a halfchair form. The ester group has an equatorial orientation. In the crystal structure, the molecules are stabil
6-Hydroxy-1H-carbazole-1,4(9H)-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that 6-hydroxy-1H-carbazole-1,4(9H)-diones would be potent antifungal age