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Synthesis and Antifungal Activity of the 2,2,5-Tetrahydrofuran Regioisomers of SCH 51048.

✍ Scribed by Raymond G. Lovey; Anil K. Saksena; Viyyoor M. Girijavallabhan; Paul Blundell; Henry Guzik; David Loebenberg; Raulo M. Parmegiani; Anthony Cacciapuoti


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
33
Category
Article
ISSN
0931-7597

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## Abstract magnified image A series of 5‐arylidene derivatives **3a‐k**, as potential antifungal agents, were synthesized in good to high yields by the reaction of 2‐benzimidazolylimino‐4‐thiazolidinone and corresponding aromatic aldehyde in a buffered medium. These compounds were evaluated for t