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Synthesis and antifungal activity of novel 2-benzimidazolylimino-5-arylidene-4-thiazolidinones

✍ Scribed by Akbar Mobinikhaledi; Naser Foroughifar; Mehdi Kalhor; Mansoureh Mirabolfathy

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
80 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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A series of 5‐arylidene derivatives 3a‐k, as potential antifungal agents, were synthesized in good to high yields by the reaction of 2‐benzimidazolylimino‐4‐thiazolidinone and corresponding aromatic aldehyde in a buffered medium. These compounds were evaluated for their antifungal activities against four agricultural fungi, Botrytis elliptica, Fusarium graminearum, Phytophthora nicotianae, and Rhizoctonia solani. Thereby, it was found that the compound 1 exhibits an antifungal effect against P. nicotianae and B. elliptica, comparable with carbendazim as a standard antifungal. Our results may provide some guidance for development of some novel benzimidazole‐based antifungal lead structures. J. Heterocyclic Chem., 2010.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis and Antif
ChemInform Abstract: Synthesis and Antifungal Activity of Novel 2-Benzimidazolylimino-5-arylidene-4-thiazolidinones.
✍ Akbar Mobinikhaledi; Naser Foroughifar; Mehdi Kalhor; Mansoureh Mirabolfathy 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis and Antifungal Activity of Som
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In continuation of our studies on the synthesis and biological activity of 4-thiazolidinone~'.~), we here report the synthesis of some hydrazones and 4-thiazolidinones carrying an imidazo[ 1.2-alpyridine moiety at the Natom, prepared with the objective of screening their antifungal activities.