Synthesis and Antidepressant Evaluation of New Hetero[2,1]benzothiazepine Derivatives
✍ Scribed by Juan A. Díaz; Salvador Vega; María A. Expósito; Candelaria C. Sánchez Mateo; Victoriano Darias
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 677 KB
- Volume
- 329
- Category
- Article
- ISSN
- 0365-6233
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## Abstract As part of an investigation directed to the search of new neurotropic agents we have prepared a number of hydroxy and hydroximino derivatives of the novel thieno and pyrazolo[2,1]benzothiazepine ring systems. Assignments of the __Z__ and __E__ hydroximino isomers were performed by study
## Abstract In this paper we describe a series of new thieno and pyrazolo[2,1]benzothiazepine derivatives **7a‐o** which were synthesized by two different methods both starting from the previously described tricyclic alcohols **1–3**. Several components of this series were effective p. o. (per os,
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