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Synthesis of new thieno and pyrazolo[2,1]benzothiazepine derivatives with potential antidepressant properties

✍ Scribed by S. Vega; J. A. Díaz; V. Darias; C. C. SÁNchez Mateo

Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
311 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

In this paper we describe a series of new thieno and pyrazolo[2,1]benzothiazepine derivatives 7a‐o which were synthesized by two different methods both starting from the previously described tricyclic alcohols 1–3. Several components of this series were effective p. o. (per os, orally) in different pharmacological tests currently employed in the evaluation of antidepressant activity.

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