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Synthesis and anticonvulsant activity of someN-(benzoyl)glycinanilide derivatives

✍ Scribed by Soyer, Zeynep; Akgul, Ozlem; Tarikogullari, Ayse H.; Calis, Unsal


Book ID
118749356
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
305 KB
Volume
22
Category
Article
ISSN
1054-2523

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Acetylenic derivatives of quinazolinones and quinazolinediones were synthesized and evaluated for their anticonvulsant activity. Most compounds displayed seizure-antagonizing activity in the maximal electroschock test (MES test) in most cases associated with little or no acute neurotoxicity determin