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Synthesis and anticonvulsant activity of novel purine derivatives

โœ Scribed by Wang, Shi-Ben; Jin, Peng; Li, Fu-Nan; Quan, Zhe-Shan


Book ID
126115398
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
652 KB
Volume
84
Category
Article
ISSN
0223-5234

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Synthesis and Anticonvulsant Activity of
โœ Cyril O. Usifoh; Gerhard K. E. Scriba ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 83 KB ๐Ÿ‘ 2 views

Acetylenic derivatives of quinazolinones and quinazolinediones were synthesized and evaluated for their anticonvulsant activity. Most compounds displayed seizure-antagonizing activity in the maximal electroschock test (MES test) in most cases associated with little or no acute neurotoxicity determin