Synthesis and Anticonvulsant Activity of
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Cyril O. Usifoh; Gerhard K. E. Scriba
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Article
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2000
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John Wiley and Sons
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English
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Acetylenic derivatives of quinazolinones and quinazolinediones were synthesized and evaluated for their anticonvulsant activity. Most compounds displayed seizure-antagonizing activity in the maximal electroschock test (MES test) in most cases associated with little or no acute neurotoxicity determin