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Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives

✍ Scribed by Li-Ping Guan; Cheng-Xi Wei; Xian-Qing Deng; Xin Sui; Hu-Ri Piao; Zhe-Shan Quan

Book ID
108116249
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
146 KB
Volume
44
Category
Article
ISSN
0223-5234

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Synthesis and Anticonvulsant Activity of
Synthesis and Anticonvulsant Activity of N-(2-Hydroxy-ethyl)amide Derivatives
✍ Li-Ping Guan; Dong-Hai Zhao; Jing-Hui Xiu; Xin Sui; Hu-Ri Piao; Zhe-Shan Quan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 363 KB πŸ‘ 2 views

## Abstract A series novel of __N__‐(2‐hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that __N__‐(2‐hydroxye