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Synthesis and Anticonvulsant Activities of N -Benzyl-2-acetamidopropionamide Derivatives

✍ Scribed by Choi, Daeock; Stables, James P.; Kohn, Harold

Book ID
117989977
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
363 KB
Volume
39
Category
Article
ISSN
0022-2623

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## Abstract A series novel of __N__‐(2‐hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that __N__‐(2‐hydroxye